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September 28th Event Sponsored by Halozyme Therapeutics

Posted by Mary Canady September 6th, 2010 .
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We’re going to try something new for the San Diego Biotechnology Network in September. The folks at Halozyme have offered to start hosting events quarterly at their site in Sorrento Valley, and we’ll kick of the first event learning about their exciting science September 28th. They focus on therapeutics that work subcutaneously by targeting the extracellular matrix (the image is from a mural in their lobby) and have had lots of great news lately, so it will be nice to hear more. As always we’ll have plenty of time for …

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SDBN August 18th Event: The Human Genome 10 Years Later: What Does it Mean for San Diego Biotech?

Posted by Mary Canady July 23rd, 2010 .
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June 2010 marks the 10th anniversary of the sequencing of the human genome. As Francis Collins has pointed out, “we invariably overestimate the short-term impacts of new technologies and underestimate their longer-term effects.” As a member of the community for 14 years, I can tell you that this is true for San Diego, as the expectations in 2000 were likely too high, but the last ten years have brought unexpected progress in many areas.
San Diego has a great ecosystem to take advantage of these exciting longer-term benefits, ranging from our …

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SDBN July 21st Speed Networking Event Sponsored by Life Technologies

Posted by Mary Canady July 1st, 2010 .
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Our January Speed Networking event went so well that we promised we’d do it again so that you can meet as many local biotech professionals as possible in one night. How does it work? Check out our report of the last speed networking event for more details, and basically show up with plenty of business cards, something to take notes with, and craft a thirty second ‘elevator speech’ which describes who you are and what you’re looking for professionally. We always have a nice mix of professionals at our events, …

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San Diego Stem Cell Coalition to Fight ALS: CIRM Update

Posted by Mary Canady June 30th, 2010 .
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The California Institute for Regenerative Medicine (CIRM) granted a local interdisciplinary research team from UCSD, Salk, and Life Technologies $11.5 million for research aimed at finding a cure for amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. On June 23rd, CIRM hosted a public research update which I attended. The project is an excellent example of local research organizations and companies working together towards translating research into real cures, funded by California citizens who realize the promise of stem cell technologies.
The ALS team is led by Lawrence Goldstein, Ph.D., and …

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#SBS10 Day 3 – Smart mice and blowing House, M.D.’s mind: Drug discovery in epigenetics

Posted by Dr. Gunn April 14th, 2010 .
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At the afternoon session of the Society for Biomolecular Science in Phoenix, it’s all about epigenetics, the study of heritable changes that don’t involve changes in genetic sequence. Epigenetics explains why identical twins turn out a little different and why even cloned cows will have different coloration patterns.

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#SBS10 report: iPS disease models coming of age for neurology

Posted by Dr. Gunn April 14th, 2010 .
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I went to a morning session on stem cells on day 2 of the Society for Biomolecular Science meeting in Phoenix, a meeting focused on advancements in drug discovery and screening technology.  After this, it’s all epigenetics.
Stephen Haggarty, Director of the Stanley Center Department of Chemical Neurology spoke on stem cells as genetically accurate disease models. The idea here is that you can take cells from a patient (and relatives) and use the clever trick first reported by Yamanaka et al. to convert skin fibroblast cells into stem cells, called …

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SBS Meeting report shows strong growth of Pubchem database #SBS10

Posted by Dr. Gunn April 14th, 2010 .
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At the 2010 Society for Biomolecular Science meeting on Tuesday, Steve Bryant from NIH gave a report on the increasing utility of the NIH Pubchem database for pharma drug screening programs.

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SBS Day Two: A Holistic Approach To Drug Discovery #sbs10

Posted by Mary Canady April 14th, 2010 .
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I’m blogging from the Society for Biomolecular Sciences conference in Phoenix, the organizers were kind enough to offer two of us complimentary passes. I was surprised that the sessions were separated into disease area, technique, or ‘phenomenon’ (e.g., epigenetics) which seemed a bit curious as well, as I had expected the different types of assay technologies would have been the basis (e.g. HTS, Cell-based). It will be interesting to see how this changes if SBS merges with ALA. Nevertheless, I’ve been spending most of my time in the oncology session, …

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Drug Discovery Channel–Welcome

Posted by Mary Canady April 11th, 2010 .
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We are launching channels on the San Diego Biotechnology Network, where local scientists and biotechnology professionals will be able to blog and discuss the topic. Our first posts will be from the Society for Biomolecular Sciences conference in Phoenix, stay tuned!

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