Home » Archive by Category

News

San Diego biotech news from BioSpace, Xconomy, PR Newswire, Marketwired and other sources, click on headlines to read the full story.

Canaan Closes $675M Fund, One Of Venture’s Ten Largest This Year

October 16, 2014 – 11:07 am | Edit Post

In a year of big venture capital numbers, Canaan Partners has provided one of the biggest. The Westport, CT-based firm announced Thursday a $675 million fund, its tenth. As with its previous general…

[[Click headline to continue reading.]]

Simplifying the Bioequivalence Testing Process and Optimizing Oral Formulation Development via Unifying the Global Life Science Community this November in San Diego

October 16, 2014 – 10:33 am | Edit Post

NEW YORK, Oct. 16, 2014 /PRNewswire/ — Curtis & Coulter LLC, a new specialty life science events organizer is under 3 weeks away from hosting their co-located Bioequivalence: Intersection Between Science & Regulatory Summit and Oral Drug Formulation Innovations Summit taking place on November 5-6 2014 at the Westin San Diego, CA.

Simplifying the Bioequivalence Testing Process and Optimizing Oral Formulation Development via Unifying the Global Life Science Community this November in San Diego

October 16, 2014 – 10:33 am | Edit Post

NEW YORK, Oct. 16, 2014 /PRNewswire/ — Curtis & Coulter LLC, a new specialty life science events organizer is under 3 weeks away from hosting their co-located Bioequivalence: Intersection Between Science & Regulatory Summit and Oral Drug Formulation Innovations Summit taking place on November 5-6 2014 at the Westin San Diego, CA.

November’s events are specifically designed to unify and assist drug development organizations in streamlining the bioequivalence testing process, as well as optimizing formulation development approaches for oral drug products. This will in turn have a positive knock-on effect on approval rates of much-needed future drug products.

“We are delighted that multiple leading players within the global life sciences community share this vision and are thrilled that attendees will be joining us in San Diego from as far afield as China, India, Taiwan, Czech Republic, Brazil, Germany and Italy,” stated Mark Coulter, CEO of Curtis & Coulter LLC. “It’s good to know the global life science community is committed to unite and work towards overcoming bioequivalence and formulation development challenges in order to ensure that faster, safer, much-needed drug products are readily available,” he added.

The two events will include key presentations from Pfizer, Merck, GlaxoSmithKline, Johnson & Johnson amongst other leading drug development organizations. Additionally presenters will include the FDA, and a number of other global regulatory agencies. You can find out more information including program details and registration options by visiting www.curtiscoulter.com

About Curtis & Coulter LLC

Curtis & Coulter specialize in researching and developing cutting-edge events for the life sciences sector. Each event is designed to bring together industry professionals in a unique format for collaborative learning and networking. They provide an unmatched, innovative user experience to exchange ideas, gain advanced industry knowledge and benchmark with like-minded peers through interactive platforms.

Media Contact:Lauren LoreyMedia@curtiscoulter.com
 631-921-9175
SOURCE Curtis & Coulter LLC

ARCS Foundation Awards $232,500 in Fellowships for UC San Diego Graduate Students

October 16, 2014 – 6:00 am | Edit Post

Dustin Richmond, a third year graduate student in computer science and engineering, builds complex computer hardware systems with the power to process large data sets—such as the data involved with DNA sequencing. In his first year, Richmond worked with technology company Cognex to design an ultra-high-speed image processing pipeline—specifically for active 3D scanners—that could decompress and process 20,000 images per second.

Robotics Legends Converge at UC San Diego Forum

October 16, 2014 – 6:00 am | Edit Post

After the industrial revolution and the Internet revolution, we are now poised for the robotics revolution. Influential robotics researchers and industry leaders made this prediction in many different ways Friday at the Contextual Robotics Technologies International Forum at UC San Diego. The speakers and more than 250 attendees gathered to reflect on what opportunities and challenges this revolution would bring, and how San Diego fits into this picture.

Changing Lives: Carol Vassiliadis Names Hospital with $8.5 Million to Jacobs Medical Center

October 16, 2014 – 6:00 am | Edit Post

Carol Vassiliadis did not attend college at the University of California, San Diego. Her two children did not go to UC San Diego. Her late husband, who battled cancer over a decade ago, was not treated at UC San Diego Moores Cancer Center. Yet, Vassiliadis has dedicated innumerable hours and considerable resources to the campus, including gifts totaling $8.5 million to the future UC San Diego Jacobs Medical Center. In honor of her support, the new facility—to be opened in 2016—will be home to the “A. Vassiliadis Family Hospital for Advanced Surgery.” A portion of Vassiliadis’ support was also matched by an anonymous donor as part of a Jacobs Medical Center Challenge grant, for a total of $12 million in gifts.

Robotics Legends Converge at UC San Diego Forum

October 16, 2014 – 6:00 am | Edit Post

After the industrial revolution and the Internet revolution, we are now poised for the robotics revolution. Influential robotics researchers and industry leaders made this prediction in many different ways Friday at the Contextual Robotics Technologies International Forum at UC San Diego. The speakers and more than 250 attendees gathered to reflect on what opportunities and challenges this revolution would bring, and how San Diego fits into this picture.

Changing Lives: Carol Vassiliadis Names Hospital with $8.5 Million to Jacobs Medical Center

October 16, 2014 – 6:00 am | Edit Post

Carol Vassiliadis did not attend college at the University of California, San Diego. Her two children did not go to UC San Diego. Her late husband, who battled cancer over a decade ago, was not treated at UC San Diego Moores Cancer Center. Yet, Vassiliadis has dedicated innumerable hours and considerable resources to the campus, including gifts totaling $8.5 million to the future UC San Diego Jacobs Medical Center. In honor of her support, the new facility—to be opened in 2016—will be home to the “A. Vassiliadis Family Hospital for Advanced Surgery.” A portion of Vassiliadis’ support was also matched by an anonymous donor as part of a Jacobs Medical Center Challenge grant, for a total of $12 million in gifts.

Novel Mutations Discovered In Cats Provide Insight Into Human Eye Diseases

October 16, 2014 – 5:30 am | Edit Post

SAN MATEO, Calif., Oct. 16, 2014 /PRNewswire/ – Researchers from the University of Missouri and the 99 Lives Cat Genome Sequencing Initiative today announced groundbreaking discoveries of novel mutations in the cat genome found to correlate to two human eye diseases, retinitis pigmentosa and Leber’s Congenital Amaurosis.  The 99 Lives Cat Genome Sequencing Initiative is a joint project between the University of Missouri, the University of California, Davis and industrial partners. The Maverix Analytic Platform was used to analyze this data, and Maverix hosts the Initiative’s genome and analysis data in a publicly-accessible “Community of Discovery.”

Leber’s Congential Amaurosis (LCA) is a rare inherited eye disease that primarily affects the retina, which is the specialized tissue at the back of the eye that detects light and color. LCA is one of the most common causes of blindness in children. With onset at birth or early in life, two to three per 100,000 newborns are born with LCA.  Persian cats can suffer from autosomal recessive progressive retinal atrophy (PRA), a disease similar to LCA. Association studies of Persian cats localized the causal gene for Persian PRA to cat chromosome E1, which is homologous to human chromosome 17. Whole genome sequencing revealed mutations in the gene AIPL1. A variety of mutations in AIPL1 have been identified as causes of various types of LCA in humans.  

By finding that the putative causative mutation for Persian PRA is in the gene that can cause LCA in humans, researchers may be able to develop models to better understand the disease pathways associated with this rare eye disease and ultimately develop diagnostic and screening tests that will improve treatment.

Retinitis pigmentosa is a condition affecting about 1 in 4,000 people in the United States. Cells in the retina controlling night vision are most likely to be affected, and symptoms include decreased vision at night or in low light, and loss of peripheral vision, commonly known as “tunnel vision.”  Symptoms often first appear in childhood but severe vision problems often do not develop before early adulthood. The whole genome sequencing of a Bengal cat found a causative genetic mutation for retinitis pigmentosa, which can serve as a model for research leading to better understanding of the causes and potential treatments for this condition in both cats and humans.

“We are thrilled that the whole genomic sequencing of cats has led to such impactful discoveries which we believe can provide an efficient and effective model for research into eye diseases affecting humans,” said Leslie Lyons PhD, Gilbreath-McLorn Professor for Comparative Medicine at the University of Missouri-Columbia. “Using whole genome sequencing enabled us to find this mutation, which would not have been possible using traditional microarray technology.”

“To whole genome sequence cats with disease traits as a routine tool will unravel simple and complex traits relevant to human health,” said Barbara Gandolfi PhD, Research Assistant Professor at the University of Missouri-Columbia. “With the help of the Maverix Analytic Platform, our first identified mutation associated with a progressive retinal atrophy in Persian cats provides a model for the study of blinding disease in humans.”

“We are pleased that the discovery of these novel mutations in cats has tremendous implications to further the understanding of LCA and retinitis pigmentosa,” said Dave Mandelkern, President and co-founder of Maverix Biomics. “We are excited that the 99 Lives Cat Sequencing Initiative is helping to advance state-of-the-art healthcare for cats as well as to help improve human health.”

Access to the 99 Lives Cat Genome Sequencing Initiative public data sets and visualization of the data within the UCSC Genome Browser are available at no cost to researchers. Performing new data analytics, exploration, or other visualization is possible for additional fees, with substantial discounts for academic and not-for-profit research organizations.

About the 99 Lives Cat Genome Sequencing InitiativeThe 99 Lives Cat Genome Sequencing Initiative is a project designed to sequence the genome of 99 cats in order to improve coverage and future assemblies of the cat genome; identify genotypic variation across a large number of cats with diverse genetic backgrounds, helping to identify causative mutations for specific health conditions in cats which may also be relevant to humans; and increase the value of individual cat genome sequencing by veterinary hospitals providing state-of-the-art health care. For more information visit http://felinegenetics.missouri.edu/ninety-nine-lives/2

About the Maverix Analytic PlatformThe Maverix Analytic Platform is a cloud-based solution designed for use directly by life sciences researchers who may not have software or bioinformatics expertise. It leverages proven open-source algorithms and applications developed at leading academic and research centers. After loading sequence data from any organism (human, animal, plant, or microbe), researchers are able to immediately perform analyses with reliable, scientifically vetted configurations, as cited in peer-reviewed journal publications. Visualization is provided through a variety of integrated graphical tools, including a private, secure version of the UCSC Genome Browser, the world’s most widely used genome browser.

About Maverix BiomicsBased in San Mateo, CA and backed by leading venture capital firms and Silicon Valley investors, Maverix Biomics, Inc. provides researchers with a cloud-based platform to manage, analyze, and visualize genomic data, build Communities of Discovery, and place their data in context with the latest public data from the full spectrum of life, including human, plant, animal, or microbial organisms. For more information, visit www.maverixbio.com.

NOTE TO REPORTERS: Barbara Gandolfi, PhD, Research Assistant Professor at the University of Missouri-Columbia will be presenting a poster on these findings from 4:00PM to 5:00PM on Sunday, October 19, 2014 in the “Molecular Basis of Mendelian Disorders” session at the 64th Annual Meeting of the American Society of Human Genetics, to be held at the San Diego Convention Center in San Diego, California. For more information or to schedule an interview with Dr. Gandolfi, please call Dave Mandelkern at 415-531-4238 or email dmandelkern@maverixbio.com.

SOURCE Maverix Biomics, Inc.

Paragon BioTeck To Exhibit At American Academy of Ophthalmology Annual Meeting In Chicago

October 16, 2014 – 5:00 am | Edit Post

PORTLAND, Ore., Oct. 15, 2014 /PRNewswire/ –Paragon BioTeck, Inc., a privately held biopharmaceutical and medical device company specializing in the development of ophthalmic pharmaceuticals, devices and therapies, will be exhibiting at the American Academy of Ophthalmology (Booth #4550) in