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Why Good Drugs Sometimes Fail: The Bexxar Story

Posted by sandiegobiotech August 26th, 2013 .
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Quite a few biotech entrepreneurs go to work each day operating under the assumption that clinical trial data is king. If you put together a rock-solid dataset from a big clinical trial that says…

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Non-Invasive Test Optimizes Colon Cancer Screening Rates

Posted by sandiegobiotech August 23rd, 2013 .
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Organized mailing campaigns could substantially increase colorectal cancer screening among uninsured patients, a study published in the August 5 online edition of JAMA Internal Medicine reveals. The research also suggests that a non-invasive colorectal…

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Immune System Molecule Promotes Tumor Resistance to Anti-Angiogenic Therapy

Posted by sandiegobiotech August 23rd, 2013 .
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A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.

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Southern California’s First Real-Time MRI-Guided Gene Therapy for Brain Cancer

Posted by sandiegobiotech August 23rd, 2013 .
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Neurosurgeons at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center are among the first in the world to utilize real-time magnetic resonance imaging (MRI) guidance for delivery of gene therapy as a potentia…

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Simple Math Sheds New Light on a Long-Studied Biological Process

Posted by sandiegobiotech August 23rd, 2013 .
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One of the most basic and intensively studied processes in biology—one which has been detailed in biology textbooks for decades—has gained a new level of understanding, thanks to the application of simple math to a problem that scientists never before thought could benefit from mathematics.

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Why Don’t We All Get Alzheimer’s Disease?

Posted by sandiegobiotech August 23rd, 2013 .
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Researchers at the University of California, San Diego School of Medicine offer an explanation for why we all don’t get Alzheimer’s disease (AD) – a trick of nature that in most people maintains critical separation between a protein and an enzyme that, when combined, trigger the progressive cell degeneration and death characteristic of AD.

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Clinical Trial Evaluates New Minimally Invasive Rectal Cancer Surgery

Posted by sandiegobiotech August 23rd, 2013 .
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Surgeons at the University of California, San Diego School of Medicine are evaluating a new, combined surgery technique to remove cancerous tumors from the rectum. The hybrid technique uses the body’s natural opening to remove malignancies and diseased tissue while also performing reconstruction.

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Mountain High: Genetic Adaptation for High Altitudes Identified

Posted by sandiegobiotech August 23rd, 2013 .
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Research led by scientists from the University of California, San Diego has decoded the genetic basis of chronic mountain sickness (CMS) or Monge’s disease.  Their study provides important information that validates the genetic basis of adaptation to high altitudes, and provides potential targets for CMS treatment.

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Preterm Babies at Risk for Later Cognitive Difficulties

Posted by sandiegobiotech August 23rd, 2013 .
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Researchers at the University of California, San Diego have received a five-year, $3 million grant from the Eunice Kennedy Shriver Institute of Child Health and Human Development, part of the National Institutes of Health. The grant will fund a longitu…

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Two Studies Identify Potential New Drug for Crohn’s Disease and Ulcerative Colitis

Posted by sandiegobiotech August 23rd, 2013 .
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Vedolizumab, a new intravenous antibody medication, has shown positive results for treating both Crohn’s disease and ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The findings, published in two papers, will appear in the August 22 issue of the New England Journal of Medicine (NEJM).

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