Guardians of the synapse: scientists identify a new role for nerve-supporting cells

LA JOLLA—Salk researchers have found, for the first time, that a blood-clotting protein can, unexpectedly, degrade nerves—and how nerve-supporting glial cells, including Schwann cells, provide protection. The findings, published March 14, 2019, in the journal PLOS Genetics, show that Schwann cells protect nerves by blocking this blood-clotting protein as well as other potentially destructive enzymes released by muscle cells. The work could have implications for diseases as diverse as amyotrophic lateral sclerosis (ALS), multiple sclerosis, Alzheimer’s disease or schizophrenia.

The post Guardians of the synapse: scientists identify a new role for nerve-supporting cells appeared first on Salk Institute for Biological Stud

Click to view original post

Advertise With Us