Scientists identify “immune cop” that detects SARS-CoV-2

Antiviral protein MDA-5 senses viral replication and governs immune response to SARS-CoV-2

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it’s time to mount an antiviral response. The study, published today in Cell Reports, provides insights into the molecular basis of severe disease and may enable new strategies for the treatment and prevention of COVID-19.

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