UC San Diego researchers have produced a single-cell chromatin atlas for the human genome. Delineating chromatin regions in cells of different human tissue types would be a major step toward understanding the role of gene regul… […]
Neuroimaging study reveals potential brain mechanism underlying chronic neuropathic pain in individuals with HIV. Findings may guide new clinical treatments targeting patients’ expectations for pain relief.
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University of California San Diego researchers, with international colleagues, describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.
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In novel study, an international research team investigated whether continued magnetic seizure therapy might effectively prevent the relapse of treatment-resistant depression, compared to what is known about electroconvulsive t… […]
International group of researchers identify new childhood genetic condition and a potential cure that can be delivered during pregnancy.
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Researchers describe how withdrawal from nicotine, methamphetamine and cocaine alters the functional architecture and patterns in the brains of mice, compared to control animals, a key to developing addiction tr… […]
From tele-monitoring patients with diabetes to using artificial intelligence to prevent sepsis, the newly launched Center for Health Innovation will seek to develop, test and commercialize technologies that make… […]
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
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Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
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Researchers identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, such as addiction. With data from 1.5 million people of European descent, the effor… […]
Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventio… […]
UC San Diego researchers identify the mutational drivers for gastrointestinal stroma tumors in the stomach and find a potential drug to treat a subset of GIST tumors afflicting the young.
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UC San Diego researchers have described a new method for observing and counting mutations in sperm, and how to use this data to predict the likely impact of these mutations on future children.
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UC San Diego researchers develop a method to grow hematopoietic stem cells in culture, with clinical implications for bone marrow transplants and aging research.
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Cardiovascular physicians with UC San Diego Health have joined an international clinical trial utilizing a new Extravascular Implantable Cardioverter-Defibrillator (EV ICD) system to help treat sudden cardiac ar… […]
Senate President Pro Tempore Toni Atkins visited UC San Diego Medical Center today to recognize a $30 million allocation in the 2021-2022 California state budget that will support the redevelopment of the new Hillcrest hospital… […]
UC San Diego researchers discovered that immunotoxins targeting the protein mesothelin prevent liver cells from producing collagen, a precursor to fibrosis and cirrhosis, in mouse models of human disease.
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Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.
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Researchers at UC San Diego School of Medicine report successfully implanting specialized grafts of neural stem cells directly into spinal cord injuries in mice, then documenting how the grafts grew and filled t… […]