LA JOLLA—Suzanne Bourgeois, PhD, Salk professor emerita, founding member of the Salk Institute, and pioneer in gene regulation research, died at her home in Del Mar, California, on March 14, 2026. She was 94 years old.
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Credit: Salk Institute
As the founder of Salk’s Regulatory Biology Laboratory, Bourgeois studied the regulation of gene expression—the process cells use to turn genes “on” or “off”—using the bacterial lactose (lac) operon as a model system. In the 1960s, when little was known about the circuit, Bourgeois demonstrated that the lac repressor was a protein. She used the system to characterize, for the first time, the interaction between a regulatory protein and DNA. She later studied gene regulation in animal cells and eventually identified compounds that could help reverse multidrug…
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