- Highlights
- Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain
- The atlas represents eight different brain regions and 36 different cell types, and shows clear epigenetic differences associated with different ages
- The new resource—available publicly on Amazon Web services—can be used to unravel age-related contributions to neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS
LA JOLLA—Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer’s to Parkinson’s to ALS and beyond, is expected to double every 20 years. Though scientists know aging is a major risk factor for neurodegenerative diseases, the full mechanisms behind aging’s impact remain unclear.
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