Curing the Bystander Effect: A New Base Editing Tool Minimizes Unwanted Edits to DNA

Base editing is still a new technology. Alexis Komor is working to improve its efficiency, while lowering unwanted bystander edits. This occurs when a base editor not only edits the desired nucleobase, but edits surrounding bases as well. Komor’s lab has developed a way to minimize bystander edits.

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