- Highlights
- Salk scientists use DNA origami technique to build dye-cycling ORBIT, a method for tracking protein-DNA interactions for hours at single base-pair resolution
- Using dye-cycling ORBIT, the team measured the rotation of RNA polymerase during DNA transcription
- The method will allow scientists to study molecular movements that were previously impossible to see or study, adding a new dimension to life science research
LA JOLLA—Scientists often describe life as a series of chemical reactions. Pallav Kosuri, PhD, describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells, and bodies—without movement, there is no life.
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