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- Highlights
- Salk scientists developed genetic tools that reveal how individual neurons control distinct, opposing behaviors in fruit flies
- The study identifies a specific group of neurons that help suppress aggression in both male and female fruit flies
- These findings provide a roadmap for understanding equivalent human neurological signaling, and help reveal how disruptions in signaling may contribute to brain dysfunction
LA JOLLA—Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave. Much of this coordination depends on neuromodulators—chemical messengers that establish how neurons communicate and function. Understanding how these signals produce distinct responses to different social contexts is crucial to understanding how the brain works.
Remarkably, many of these fundamental molecular mechanisms are conserved across evolution, including in the tiny brain of a fruit fly. That makes fruit flies powerful…
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